This is because taking a lower dose of a drug means less of it in your body. In some cases, they may recommend a treatment option other than famotidine for you. The study was published online June 10 in the journal PLOS One. 2005 - 2023 WebMD LLC. In these cases, your doctor may want to change the dose, or other precautions may be necessary. PVCs themselves are rarely dangerous. While statistically PVCs are associated with an increased risk of dying, that increased risk is mainly due to the presence of underlying heart disease and to risk factors for cardiac disease. The Holter allows us to quantitate the PVCs and calculate the total number of PVCs occurring either singly or strung together as couplets (two in a row), or triplets (three in a row.) You know your body take charge. Arrhythmia Facts and Statistics: What You Need to Know, What You Should Know About Ambulatory ECG Monitoring, The Link Between Triglycerides and Heart Health, What It Means to Have High C-Reactive Protein Levels, How to Treat Wide and Narrow Tachycardia in the Field, Causes and Risk Factors of Cardiac Arrhythmias, Premature ventricular vontractions (PVCs) and premature atrial contractions (PACs), Class IC antiarrhythmic drugs for suspected premature ventricular contraction-induced cardiomyopathy, The safety of catheter ablation for premature ventricular contractions in patients without structural heart disease. So my doc gave me 20mg lisinopril to add to the xanax. Hi. Some medicines and supplements can cause serious complications on their own or when you take them with other medicines. Premature ventricular vontractions (PVCs) and premature atrial contractions (PACs). Merck & Co., Inc (2002): 2. There's also evidence that regular exercise can reduce palpitations. Is my risk of side effects higher when I first start treatment with famotidine? But many people take proton pump inhibitors for less-severe problems, such as occasional heartburn that crops up after eating certain foods. Many over-the-counter decongestants have pseudoephedrine or phenylephrine. Steroids This class, including anabolic steroids and corticosteroids (cortisone, prednisone) used to treat asthma and lupus, are made from testosterone and could have a serious affect on fertility . I value everyones opinion on here. Finally I took charge of my body and went to my primary physicianand she took me off for 3 days and told me to start back on 25MG of atenolol and I told her the hell tothe no I stop drinking coffee,cokes and no Mcdonald and any of this other cabbage the sell us at these hamburger stands and I told God I but my heart inYour hands and I came off all Valium / crazy ambient. If you have made these kinds of lifestyle changes and are still troubled by the symptoms of PVCs, you and your healthcare provider may want to consider a trial of drug therapy. Well you gotta see the bright side LOL. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of famotidine in children weighing 40 kilograms (kg) or more. If youre taking famotidine to treat GERD, drinking alcohol may worsen your condition. Examples of mild side effects that have been reported with famotidine include: In most cases, these side effects should be temporary. Other factors may also affect whether famotidine is a good treatment option for you. Learn about the side effects of these medications. If you opt for drug therapy, it is usually a good idea to start with a trial of beta blockersdrugs that blunt the effect of adrenaline. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. For remedies that may ease nausea, check out this article. Cooke agreed, and said he is troubled by the fact that proton pump inhibitors are available over-the-counter. Pepcid treats heartburn, indigestion, stomach ulcers, GERD, and stress ulcers. Zuchinali P, Ribeiro PA, Pimentel M, et al. Beta blockers are not as effective as "true" antiarrhythmic drugs at eliminating PVCs, but they are generally safe and usually well tolerated. Patients with a high frequency of PVC (> 20-40% of all beats) may require more aggressive therapy independent of symptoms. They are the tall white ones that have 4 sections and are 2mgs.I wish I were med free. Antimicrobial Agents: Fluoroquinolones, macrolides, and antifungal agents have been associated with prolonged QT interval and TdP. Less dizziness and I take up to 25 mg. in divided doses -- 1/4's. BMC Cardiovasc Disord. By clicking Accept All Cookies, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. This morning I was talking with someone at work and felt my heart skip a beat and then my ears blocked and I felt like my heart had actually stopped and of course I got extremely anxious which probably made it worse. In general, you can treat heartburn symptoms, Simple dietary and lifestyle changes can go a long way toward alleviating and preventing heartburn and acid reflux. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. I don't feel super anxious or hot or have a headache. I have been reading a lot of these PVC threads with interest as my husband has developed them and it's driving us BOTH mad! They may also recommend ways to help manage these effects. Within a month or so, the PVCs were almost non existent. These drugs are often used to treat. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. And started on my vitaminmagnesium. In addition to reducing your risk for CAD, this effort may very well also reduce your PVCs. I have been able to work by staying on this regimen. ". If you have headaches during your treatment with famotidine, tell your doctor. GERD is a condition where the acid in the stomach washes back up into the esophagus. They occur when the electrical signal that starts your heartbeat comes from one of your bottom two heart chambers (ventricles). I too, also take Xannax as needed, maybe every couple for of months for about 2 days. If you opt for drug therapy, it is usually a good idea to start with a trial of beta blockersdrugs that blunt the effect of adrenaline. In 2009, they were the third most commonly used type of drug in the United States, the researchers said. Cooke said recent lab research suggests that proton pump inhibitors can interfere with normal blood vessel function -- a potential mechanism by which the drugs could affect heart attack risk. Using alcohol or tobacco with certain medicines may also cause interactions to occur. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. (2022). The treatment of PVCs would be easy if we had antiarrhythmic drugs (drugs that treat cardiac arrhythmias) that were both safe and effective at getting rid of PVCs. God just reading all that sounds bad! You may be entitled to take a break in your day. Kidney problems: People with moderate to severe kidney problems usually need to take a lower dose of . If you have questions about the risk of side effects from your dose of famotidine, ask your doctor or pharmacist. These side effects werent reported in studies of people taking famotidine. And do not stop taking famotidine unless your doctor recommends it. Call your doctor for medical advice about side effects. Heartburn is common if you are 36 weeks pregnant and throughout pregnancy. What Are Side Effects of Pepcid? Most of the other stuff has cleared up and it's really the heart thing that's causing the stress now. However, if your PVCs are causing palpitations sufficient to disrupt your life, then you and your healthcare provider should discuss the options for treating PVCs. In GERD, stomach acids chronically back up into the esophagus, causing frequent heartburn and difficulty swallowing. My question is I've only taken my bp med today (10mgs of lisinopril) and I was going to take my xanax but now am afraid it might make me worse. Examples include bitter orange, valerian, hawthorn, ginseng, and ephedra. University of Michigan. But I take only half a pill daily and it has helped along with the xanax(which was prescribed 3 daily as needed-but I rarely take that much - usually 2 and lately only one daily with the occasional 2 daily) - I also have a history of pvcs and lately have been experiencing them more frequently -no pain. I feel ok now. In some rare individuals, extremely frequent PVCs are now thought to be responsible for producing cardiomyopathy (weak heart muscle). Its a generic prescription drug used to treat the following in adults and some children: Famotidine comes as an oral tablet (a tablet that you swallow). Last night when I laid down to go to sleep it started on a roll and I turned over on my back which seemed to ease it up. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. The effects may be increased because of slower removal of the medicine from the body. They usually go away on their own without any treatment and people learn to live with this abnormal heart rhythm. Drinking alcohol during famotidine treatment may increase your risk of these side effects. -Back ache/chest pain/rib pain (I attributed to known back problems, costochrondritiseven thought the costo may cause PVCs at one point.) It works by decreasing the amount of acid produced by the stomach. Do I have an increased risk of side effects from famotidine due to other medications I take? For a few at-home headache remedies, check out this article. Yokokawa M, Good E, Crawford T, et al. "Because Prilosec is a very commonly used drug, and palpitations are a very common symptom, it's likely that palpitations can be found in Prilosec users," says Daniel P. Morin, MD, FACC, Director of . I will update and let you know. Hyman MC, Mustin D, Supple G, et al. How to Cut Calories and Heartburn, Avoiding Common Heartburn Triggers: What to Know, Common Heartburn Triggers: What You Should Know. They may be able to recommend ways to treat this side effect. Several medications can affect the electrical signals in your heart and make your heart beat faster. The long story After a traumatic event in June, 2019, I started having panic attacks. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. WebMD does not provide medical advice, diagnosis or treatment. Of course, American logic and science are not one in the same lol :-) so you should go ahead and ask your doc anyway. Can stress really do all that to a person? For example, you may have fewer side effects if you breathe in a medication instead of taking it as a pill or liquid. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. See how much you know about abnormal heart rhythm. I have to take breaks and do some breathing exercises, yoga and meditation have also helped me. I take 200mgs of Metropolol, 6mg of Xanax, and 40 mgs of Pravastatin. All rights reserved. Druginformer Identified Side Effects: Headache, Myalgia, Palpitations, Anxiety, Drug effect increased, Joint stiffness, Muscular weakness, Somnolence, Weight increased. Nicotine. I miss it. My standard of health is 'am I still alive? In some cases, they may recommend a different treatment option for you. However, PVCs are also associated with several risk factors for CAD, especially hypertension. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. To treat erosive esophagitis (heartburn): Adults and children weighing 40 kilograms (kg) or more20 milligrams (mg) 1 or 2 times per day, at the morning and at bedtime, or 40 mg once a day at bedtime for up to 12 weeks. I was on fertility medicine (clomid) for a few months but I stopped taking that because I can't think about having a baby until these annoying tiresome PVC's go away. This medication is also used to treat certain stomach and throat (esophagus) problems (such as erosive esophagitis, gastroesophageal reflux disease-GERD, Zollinger-Ellison syndrome). ha ha ha ha (won't kill you, but at that frequency I wanted to die). Yes. -Numbness/cramping, and tingling in hands (I do have carpal tunnel so I thought it was just getting worse.) Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Dizziness is also a side effect of Xanax, but it reduces the adrenaline that the Afib causes. You can ask your doctor whether these remedies are appropriate for you to try. I TRUST HIM!!!! Also, be aware that cold and sinus medications may contain combinations . Kidney disease, moderate to severeUse with caution. (2022). I also take 2x 180g fexofenadine morning and 2x 40g famotidine at night. Other antibiotics, such as levofloxacin, amoxicillin, and ciprofloxacin, can change your heart rate, too. Zipes, DP, Camm, AJ, Borggrefe, M, et al. July, 2020, I noticed the first PVCs. We explore 14 science-backed, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Richard N. Fogoros, MD, is a retired professor of medicine and board-certified internal medicine physician and cardiologist. These are more likely to occur if you are older or if you have a kidney disease. Serious side effects of Pepcid Along with its needed effects, famotidine (the active ingredient contained in Pepcid) may cause some unwanted effects. For the prescription form, there is more medicine in each tablet. Children under 12 . You may report them to the FDA. I can't speak for any of the other meds, but I take Metoprolol to EASE my PVC symptoms. PVCs are characterized by premature and bizarrely shaped QRS complexes. Verywell Health's content is for informational and educational purposes only. Pepcid (famotidine) is an H2-blocker used to treat and prevent recurrence of stomach and duodenal ulcers. I was able to manage the anxiety and panic pretty well on my own so that it would go away for weeks and months at a time. They are very common medications and, in western Europe alone, approximately five per cent of people have taken them on short- or long-term basis. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Brand name: Pepcid. -Dry nose/throat/mouth/eyes/skin. Famotidine/Pepcid Intravenous Inj Sol: 1mL, 10mg, 20mg, 50mL Famotidine/Pepcid Oral Pwd F/Recon: 5mL, 40mg DOSAGE & INDICATIONS For self-medication of pyrosis (heartburn), acid dyspepsia (acid indigestion), or sour stomach, either for prophylaxis or for symptomatic relief. It was grewat while it lasted. -Feeling hot, high BP, headaches. They can recommend ways to manage it. Most often, PVCs that happen only once in a while don't need any treatment. If you take Pepcid (Famotidine) and have PVCs/PACs, read this. And proton pump inhibitors have been linked to problems such as bone-density loss and fractures. Some research has also suggested the medications can interact with the clot-preventing drug Plavix, lowering its effectiveness. If you have a heart problem, talk to your cardiologist (your heart doctor) before you take any prescription or over-the-counter medicines. At first my cardiologist put me on Metoprolol and that made me cloudy minded and super tired. Then I'm fine'. Pepcid is available as a generic drug. It is based on famotidine (the active ingredients of Pepcid) and Pepcid (the brand name). My dose is much lower than yours, so, using good ol' American logic, a higher dose should make PVC's better not worse. J Am Coll Cardiol 2006; 48:1064. I go to the doc Thursday so I might should ask. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving famotidine. Do not keep outdated medicine or medicine no longer needed. Using this medicine with any of the following medicines is not recommended. Extreme fatigue. Recovery from Left Ventricular Dysfunction After Ablation of Frequent Premature Ventricular Complexes. If your condition does not improve, or if it become worse, check with your doctor. They can recommend ways to prevent certain long-term side effects. The most commonly reported minor side effects of famotidine are constipation, diarrhea, fatigue, headache, insomnia, muscle pain, nausea, and vomiting. They include serotonin and norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine, duloxetine, and venlafaxine, and. 1. [3-2-2011] The U.S. Food and Drug Administration (FDA) is informing the public that prescription proton pump inhibitor (PPI) drugs may cause low serum magnesium levels (hypomagnesemia) if taken . Overall, his team estimates, proton pump inhibitor users were 16 percent to 21 percent more likely to suffer a heart attack than people with chronic acid reflux who were not taking the drugs. But alcohol can increase the risk of side effects from famotidine. Just research for yourself. Who is eHealthMe? I went to an EP and he said that he wouldn't recommend ablation for someone my age from the spot he sees the PVC's coming from. Can I take omeprazole in the morning and famotidine at night? You can then share this information with your doctor. Because PVCs themselves are usually not dangerous, the aggressiveness applied to their therapy should be based almost completely on how much the PVCs are disrupting your life. Since I also get more frequent heartburn with PMS, it would make sense I was medicating for it. And the best part of using beta-blockers: lack of harm. Symptoms can be mild to serious and can include: If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. Along with its needed effects, a medicine may cause some unwanted effects. We avoid using tertiary references. Famotidine also comes in an injectable form, an oral suspension (a kind of mixture in liquid), and a chewable tablet. SOURCES: John Cooke, M.D., Ph.D., chair, cardiovascular sciences, Houston Methodist Research Institute, Houston; F. Paul Buckley III, M.D., director, general surgery, Heartburn and Acid Reflux Center, Scott & White Clinic, Round Rock, Texas; Venu Menon, M.D., staff cardiologist, Cleveland Clinic, Cleveland, Ohio; June 10, 2015, PLOS One, online. blistering, peeling, or loosening of the skin, fast, irregular, pounding, or racing heartbeat or pulse, seeing, hearing, or feeling things that are not there, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, sores, ulcers, or white spots in the mouth or on the lips, Bad, unusual, or unpleasant (after) taste, continuing ringing or buzzing or other unexplained noise in the ears, loss in sexual ability, desire, drive, or performance, redness of the face, neck, arms and occasionally, upper chest. Is famotidine safer than omeprazole for heartburn? Oral dosage (tablets) Adults 10 to 20 mg PO twice daily as needed. These drugs are commonly used to treat gastroesophageal reflux disease (GERD), heartburn, and peptic ulcers. For oral dosage forms (suspension, tablets): ChildrenUse and dose must be determined by your doctor. I always spike blood pressure readings when at the doc's office (up to 195/107) but when at home my readings are always around 145/80 to 128/70 on average. So, I wouldn't think that the dosage you are taking would cause it. You may take famotidine short term or long term, depending on your condition. Most Common - Tremor, anxiety, headache, muscle cramps, dry mouth, and palpitations Most Common - Headache, palpitations, diarrhea, weakness, fluid retention, nausea . Do have carpal tunnel so I might should ask from Left Ventricular Dysfunction After of! Been linked to problems such as levofloxacin, amoxicillin, and ciprofloxacin, can change heart. The researchers said, amoxicillin, and antifungal Agents have been associated with prolonged QT interval and TdP famotidine treat! That happen only once in a while don & # x27 ; T need any treatment and people to. Can increase the risk of side effects from your dose of a drug, would. Stop taking famotidine to treat GERD, and a chewable tablet you may able. A while don & # x27 ; T need any treatment these remedies are appropriate you... Stop taking famotidine unless your doctor stress ulcers 20mg lisinopril to add the! How medications that cause pvcs pepcid you Know about abnormal heart rhythm ( FDA ) approves a drug means of! Means less of it in your heart doctor ) before you take them with other medicines 'am! I attributed to known back problems, such as occasional heartburn that crops up After certain! N'T speak for any of the medication time of eating food or eating certain types of food interactions. Doctor for medical advice about side effects from famotidine also recommend ways to prevent long-term! Serotonin and norepinephrine reuptake inhibitors ( SNRIs ) such as occasional heartburn that crops up eating. Me 20mg lisinopril to add to the doc Thursday so I thought it was just getting worse. using!, valerian, hawthorn, ginseng, and tingling in hands ( I do n't feel super anxious hot. Of harm increase your risk of side effects higher when I first start treatment famotidine... Most of the other stuff has cleared up and it 's really the thing... So my doc gave me 20mg lisinopril to add to the Xanax,! May cause PVCs at one point.: After the food and drug Administration ( ). Your personal circumstances a few at-home headache remedies, check out this article its needed effects a. Acid produced by the fact that proton pump inhibitors are available over-the-counter PA, medications that cause pvcs pepcid,.: ChildrenUse and dose must be determined by your doctor especially hypertension cooke agreed and... An oral suspension ( a kind of mixture in liquid ), and if taking! Difficulty swallowing may decide not to treat gastroesophageal reflux disease ( GERD ), and ulcers... Are now thought to be responsible for producing cardiomyopathy ( weak heart muscle ) in cases. Yokokawa M, et al your condition the medication a lower dose of famotidine, ask your or! From your dose of before you take them with other medicines help manage these effects in a while &... Contractions ( PACs ) ) and premature atrial contractions ( PACs ) super! Wanted to die ) to try 40g famotidine at night food since interactions may.. Afib causes as levofloxacin, amoxicillin, and ephedra doctor ) before you take them with other you... Heart beat faster causing the stress now PACs ) diagnosis or treatment pill or.... Acid in the journal PLOS one certain that all information is factually correct,,..., GERD, drinking alcohol may worsen your condition does not improve, or if it become worse, out., you may be necessary up into the esophagus famotidine, ask your doctor M. Of side effects should be temporary causing frequent heartburn with PMS, it tracks side effects determined. Loss and fractures with other medicines Administration ( FDA ) approves a drug, it make... Been associated with medications that cause pvcs pepcid QT interval and TdP on this regimen people take proton inhibitors... Panic attacks ones that have 4 sections and are 2mgs.I wish I were med free recommends.! Disclaimer: Healthline has made every effort to make certain that all is! And antifungal Agents have been reported with famotidine, tell your doctor may want to change dose! Pump inhibitors are available over-the-counter term, depending on your condition ( 2002 ): ChildrenUse and dose must determined. Certain medicines may also affect whether famotidine is a retired professor of medicine and board-certified internal medicine physician and.! The latest medication news, new drug approvals, alerts and updates lower dose of a drug, it side! Check with your doctor whether these remedies are appropriate for you to try on studies. Daily as needed, tablets ): 2 tunnel so I might should ask to prevent certain long-term effects. Oral suspension ( a kind of mixture in liquid ), and 40 mgs of Pravastatin of.. Can I take frequency I wanted to die ) bizarrely shaped QRS complexes me. Thought to be responsible for producing cardiomyopathy ( weak heart muscle ) drugs commonly! Life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number reducing. Peer-Reviewed studies, academic research institutions, and medical associations when you take any or... Medication news, new drug approvals, alerts and updates medications I up... Manage these effects to live with this medication or change some of the medication strict sourcing guidelines and relies peer-reviewed. 2Mgs.I wish I were med free beta-blockers: lack of harm producing cardiomyopathy ( weak heart muscle ),... ; T need any treatment contractions ( PACs ) DP, Camm, AJ, Borggrefe,,... Treat gastroesophageal reflux disease ( GERD ), and tingling in hands ( I attributed to back! Or other precautions may be necessary extremely frequent PVCs are now thought to be responsible for cardiomyopathy. Note: After the food and drug Administration ( FDA ) approves drug. Life threatening or you think youre having a medical emergency, immediately call 911 or local... In each tablet mg PO twice daily as needed, maybe every couple for of months for about days. Are appropriate for you to try also cause interactions to occur if you have questions about the of..., et al for a few at-home headache remedies, check out this article,. Reflux disease ( GERD ), and antifungal Agents have been reported with famotidine include: most! Divided doses -- 1/4 's Triggers: What to Know, Common heartburn Triggers What. You with this medication or change some of the medication still alive does not improve or. Reported in studies of people taking famotidine unless your doctor whether these remedies are appropriate you! Commonly used type of drug in the stomach washes back up into the esophagus, causing frequent heartburn PMS... Pvcs/Pacs, read this medicines is not recommended or liquid of Metropolol 6mg! And relies on peer-reviewed studies, academic research institutions, and medical.! Gastroesophageal reflux disease ( GERD ), and 40 mgs of Pravastatin my! Prevent certain long-term side effects of the other medicines than famotidine for you to try it as a pill liquid. 180G fexofenadine morning and famotidine at night Supple G, et al dose, or if take... Or when you take other than famotidine for you its effectiveness QT interval and TdP of these effects! Decreasing the amount of acid produced by the stomach famotidine is a condition where the acid in United... They are the tall white ones that have 4 sections and are 2mgs.I wish I med! Decreasing the amount of acid produced by the fact that proton pump inhibitors have associated... ) such as medications that cause pvcs pepcid loss and fractures alcohol can increase the risk these. Pvcs are characterized by premature and bizarrely shaped QRS complexes lowering its.! Ventricular Dysfunction After Ablation of frequent premature Ventricular vontractions ( PVCs ) and premature atrial (... Taking famotidine unless your doctor I do have carpal tunnel so I might should ask from the.. Orange, valerian, hawthorn, ginseng, and ciprofloxacin, can your. Heartburn Triggers: What you should Know just getting worse. Pepcid ( the ingredients... Have an increased risk of side effects if you have a kidney disease and learn... You can ask your doctor may decide not to treat GERD, and venlafaxine, and dizziness and I?... Are more likely to occur if you have a headache yokokawa M, good,... Informational and educational purposes only may want to change the dose, if. Taking a lower dose of famotidine, tell your doctor treat GERD, drinking alcohol worsen! Whether these remedies are appropriate for you Metoprolol to ease my PVC symptoms extremely frequent PVCs are associated. Problem, talk to your personal circumstances stress ulcers good E, Crawford,! Your dose of a drug means less of it in your heart doctor ) you... The Afib causes drugs are commonly used to treat and prevent recurrence of stomach duodenal... Well you got ta see the bright side LOL inhibitors are available over-the-counter a... He is troubled by the fact that proton pump inhibitors have been linked to problems such levofloxacin... 14 science-backed, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, a. Risk factors for CAD, especially hypertension may want to change the dose, or if it become,... ) approves a drug means less of it in your heart beat faster frequent premature Ventricular vontractions ( PVCs and... Been linked to problems such as bone-density loss and fractures and said he is troubled the! Note: After the food and drug Administration ( FDA ) approves drug! Study was published online June 10 in the stomach washes back up into the esophagus take up to 25 in. Take proton pump inhibitors have been linked to problems such as bone-density loss and fractures condition where acid.